Description
Biotin from Stexol Chemicals is pure D-Biotin (INCI: Biotin; CAS 58-85-5; also called Vitamin B7 or Vitamin H). cdhfinechemical It is a white crystalline powder made and supplied with a minimum assay of 98.5% on the dried basis, in line with the European Pharmacopoeia monograph (98.5–101.0%) and the USP/FCC specifications. bucktonscottuspbpep Its quality matches well-known brand grades such as dsm-firmenich D-Biotin, so you can use it in your current formula without changing anything. You simply get the same active at a better price.
In finished products, Biotin is the ingredient behind the “biotin-enriched” claim that Pakistani consumers look for on shampoo, hair oil and serum shelves. It is listed as a hair conditioning agent and skin conditioning agent. cir-safetycir-safety dsm-firmenich describes biotin as improving the quality of keratin structures, with a positive effect on fine and brittle hair and nails. ulprospectordsm-firmenich Very little is needed: typical use levels are a fraction of a percent.
Its most important technical feature is solubility, and this is where many biotin batches go wrong. According to Sigma-Aldrich’s Biotin datasheet, D-Biotin dissolves only 22 mg per 100 mL of water at 25 °C (roughly 0.02%), compared with 10 mg/mL in 0.1 M sodium hydroxide, so it dissolves readily in warm water and dilute alkali. Once dissolved, it is unusually tough for a vitamin. US Biological’s datasheet says biotin “is stable at 100°C in moderately acid or neutral aqueous solutions” and that solutions above pH 9 are less stable. You can add it to your hot water phase instead of waiting for the cool-down. If you handle it correctly, you get a clear, grit-free product. If you don’t, you get white specks at the bottom of the bottle.
The Reason Why Formulators Would Use Biotin
The “Biotin-Enriched” Claim with One Ingredient: “Biotin” is one of the most-searched ingredient names in Pakistani hair care. One small addition lets you put it on the front label of a shampoo, conditioner, hair mask or scalp serum and build a whole range around it.
Real Pharmacopoeia-Grade Purity, Not a Diluted Powder: A lot of “biotin powder” sold online is a 1% or 2% trituration, meaning biotin spread on a carrier such as dicalcium phosphate (typical spec: 0.9–1.1% biotin). parchem Those grades are made for supplements and feed. watson-inc The carrier does not dissolve, so it clouds clear shampoos and serums, and you pay for 98–99% filler. Stexol supplies the pure crystalline grade, so 1 g in your formula really is about 1 g of biotin.
Heat-Stable in the Water Phase: Unlike heat-sensitive actives such as Vitamin C, biotin in solution holds up at 100 °C within pH 4–9. sciencedirect It can go into the heated water phase of creams and conditioners, which helps it dissolve. Hot-process manufacturers do not need a separate cold-mix step.
Works in Low Doses: In the cosmetics industry survey reported by the Cosmetic Ingredient Review (CIR), shampoos used biotin at 0.001–0.01%, and the maximum leave-on level was 0.1%. cir-safety +2 A 1 kg pack treats hundreds of kilograms of finished product, so the cost per bottle is very small.
Brand-Grade Quality at a Local Price: Imported brand-grade D-Biotin usually comes through distributors with sample request forms, business-email requirements and long lead times. dsm-firmenich Stexol keeps Biotin in stock in Pakistan, made to the same pharmacopoeia specs, at a price that suits local manufacturers.
Pairs Well with Common Hair-Care Ingredients: Biotin is commonly formulated with panthenol (Pro-Vitamin B5), niacinamide, caffeine, hydrolysed keratin and other proteins, and amino acids. bioshop Biotin, panthenol and caffeine is a classic scalp-care trio, and Stexol can supply all of them in one order.
How to Use Biotin
Handling Note:
Biotin is a fine, white, odourless crystalline powder. It does not dissolve in oils and dissolves only slightly in cold water (about 0.02%), so never add it dry to a finished batch or an oil phase. sdfinebulknaturalswholesale Use one of these methods:
Warm-water method (most common): Disperse Biotin in part of the formula water heated to 70–75 °C and stir until clear. bulknaturalswholesale For levels up to about 0.05% this is usually enough.
Mild-alkali method (for 0.05–0.1% or clear products): Disperse Biotin in water and add a few drops of 10% sodium hydroxide, triethanolamine or L-arginine solution until the pH reaches about 6.5–7.0. The biotin turns into its soluble salt form and the solution clears. service +3 Then add this premix to the main water phase.
Glycol premix: For serums and tonics, slurry Biotin in propylene glycol or butylene glycol, then add it to the warm water phase while stirring.
Keep the working pH between 4 and 9. Biotin is stable in that range, but solutions above pH 9 are less stable. usbio Avoid strong oxidising agents such as hydrogen peroxide in bleach or developer systems, and formaldehyde-releasing preservatives, because these can degrade biotin. chemicalbook Dry biotin is fairly stable to air, daylight and heat, but UV slowly breaks it down. sagepubsigmaaldrich Keep the container tightly closed, away from moisture and direct sunlight, and package the finished products in opaque or UV-protective containers. bulknaturalswholesale
Product Type Levels of Usage:
Target pH: Biotin is stable at pH 4–9. Most hair and skin products containing it are finished at pH 4.5–6.5, which suits scalp and hair. When using the mild-alkali method, dissolve Biotin at pH 6.5–7.0 first, then adjust the finished batch to the target pH. At these low levels it stays in solution well in most surfactant and emulsion bases. Always confirm stability at your final pH with a test batch.
| Product Type | Biotin in Formula (by weight) |
| Shampoo / Anti-Breakage Shampoo | 0.01% – 0.1% |
| Rinse-Off Conditioner | 0.02% – 0.1% |
| Hair Mask / Deep Treatment | 0.05% – 0.2% |
| Leave-In Serum / Scalp Tonic | 0.05% – 0.1% |
| Face Cream / Face Serum | 0.01% – 0.1% |
| Body Lotion | 0.01% – 0.05% |
| Nail Serum / Cuticle Treatment | 0.05% – 0.1% |
For hair oils: Biotin does not dissolve in oils. Either make a bi-phase (oil + water) product with Biotin in the water layer, or label the oil as “biotin-infused” only if you have a stable dispersion. Do not just stir powder into oil. bulknaturalswholesale
Formulation Build Order:
Heat the formula water to 70–75 °C (for emulsions, heat the water phase).
Disperse Biotin in part of the hot water, or in the glycol premix, and stir until fully clear. Use the mild-alkali method if needed.
Add the water-phase ingredients: glycerin, panthenol, niacinamide, chelating agent, and cationic polymers (for conditioners).
For shampoos, add the primary surfactant (e.g., SLES), then the secondary surfactant (e.g., CAPB). For emulsions, emulsify the oil phase into the water phase.
Cool below 40 °C, then add heat-sensitive extras: caffeine solution, hydrolysed keratin, fragrance and preservative.
Adjust pH to target (4.5–6.5) and thicken with salt or polymer.
Run a 24-hour check for clarity, sediment and pH before filling.
What You Can Make With Biotin
Biotin shampoos and anti-breakage shampoos
Biotin conditioners and hair masks
Leave-in hair serums and scalp tonics
Biotin + caffeine + panthenol scalp treatments
Bi-phase biotin hair oils
Nail strengtheners and cuticle serums
Face creams, serums and body lotions with B-vitamin complexes
Beard washes, beard serums and men’s grooming lines
Why Order From Stexol?
COA By Batch: Every shipment comes with a Certificate of Analysis showing assay, specific optical rotation (+89° to +93°), loss on drying and appearance for that batch. anmolfishersci You can see the purity before the powder goes into your tank.
There is No Minimum Order Pressure: Need [smallest pack size, e.g., 25 g / 100 g] for lab trials or [1 kg / 5 kg / 25 kg] for production? Order what your batch needs. Small brands and large manufacturers get the same grade.
Discounted Pricing on Bigger Orders: Tiered pricing applies as volumes increase. Send your required quantity on WhatsApp at +92-316-0099118 and get a quote the same day.
Same-Day Dispatch: Orders confirmed and then gets dispatched the same day from warehouse, with delivery across Pakistan, including Karachi, Lahore, Islamabad, Faisalabad and other cities.
Frequently Asked Questions
Q: Is Stexol’s Biotin the same as brand-name D-Biotin grades like dsm-firmenich? A: Yes, in specification. Stexol’s Biotin is pure D-Biotin (CAS 58-85-5) at a minimum 98.5% assay, which meets the European Pharmacopoeia limits (98.5–101.0%) used for leading brand grades. It is not a 1% or 2% trituration on a carrier. The batch COA confirms the assay.
Q: Why won’t my Biotin dissolve, and can I add it while the batch is hot? A: Biotin dissolves only about 0.02% in cold water, so dry powder added at room temperature leaves specks. researchgate Dissolve it in hot water (70–75 °C) or raise the premix pH to about 6.5–7.0. Adding it hot is fine, because biotin solutions are stable at 100 °C within pH 4–9.
Q: Will Biotin make my shampoo grow hair? A: Biotin is a recognised hair and skin conditioning ingredient, and its main commercial value is the “biotin-enriched” positioning consumers ask for. Clinical evidence for hair growth is limited. US FDA regulation 21 CFR 310.527, which names biotin and all other B-vitamins, states that “any OTC drug product for external use containing an ingredient offered for use as a hair grower or for hair loss prevention cannot be considered generally recognized as safe and effective for its intended use.” We recommend label claims such as “biotin-enriched”, “strengthening care for fine, brittle hair” or “reduces breakage from combing” (only with your own testing), rather than growth or hair-loss claims.
Q: How should Biotin be stored, and what is the shelf life? A: Store it tightly closed in a cool, dry place below 25 °C, away from direct sunlight and moisture. bioshop Shelf life is [24–36] months from manufacture in the unopened original pack. Check the date on your COA.
Q: Can Biotin be combined with panthenol, niacinamide, caffeine, keratin or other actives? A: Yes. Biotin is routinely formulated with panthenol, niacinamide, caffeine, hydrolysed proteins, amino acids, SLES/CAPB surfactant systems and cationic conditioning polymers. Avoid strong oxidisers (peroxide-based systems) and formaldehyde-releasing preservatives, and stay between pH 4 and 9. bioshop
Order Now
Stexol Chemicals supplies pure D-Biotin (≥98.5%) in [25 g / 100 g / 500 g / 1 kg / 5 kg / 25 kg] packs, with a batch COA and same-day dispatch on orders after confirmation. Bulk orders get tiered discounts. Message us on WhatsApp at [+92-316-0099118] for today’s price and stock.





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